diff --git a/llama_stack/providers/remote/vector_io/milvus/milvus.py b/llama_stack/providers/remote/vector_io/milvus/milvus.py
index 5e217bb55..383fa517a 100644
--- a/llama_stack/providers/remote/vector_io/milvus/milvus.py
+++ b/llama_stack/providers/remote/vector_io/milvus/milvus.py
@@ -52,11 +52,13 @@ class MilvusIndex(EmbeddingIndex):
         collection_name: str,
         consistency_level="Strong",
         kvstore: KVStore | None = None,
+        parent_adapter=None,
     ):
         self.client = client
         self.collection_name = sanitize_collection_name(collection_name)
         self.consistency_level = consistency_level
         self.kvstore = kvstore
+        self._parent_adapter = parent_adapter
 
     async def initialize(self):
         # MilvusIndex does not require explicit initialization
@@ -64,15 +66,36 @@ class MilvusIndex(EmbeddingIndex):
         pass
 
     async def delete(self):
-        if await self.client.has_collection(self.collection_name):
-            await self.client.drop_collection(collection_name=self.collection_name)
+        try:
+            if await self.client.has_collection(self.collection_name):
+                await self.client.drop_collection(collection_name=self.collection_name)
+        except Exception as e:
+            logger.warning(f"Failed to check or delete collection {self.collection_name}: {e}")
 
     async def add_chunks(self, chunks: list[Chunk], embeddings: NDArray):
         assert len(chunks) == len(embeddings), (
             f"Chunk length {len(chunks)} does not match embedding length {len(embeddings)}"
         )
 
-        if not await self.client.has_collection(self.collection_name):
+        try:
+            collection_exists = await self.client.has_collection(self.collection_name)
+        except Exception as e:
+            logger.error(f"Failed to check collection existence: {self.collection_name} ({e})")
+            # If it's an event loop issue, try to recreate the client
+            if "attached to a different loop" in str(e):
+                logger.warning("Recreating client due to event loop issue")
+
+                if hasattr(self, "_parent_adapter"):
+                    await self._parent_adapter._recreate_client()
+                    collection_exists = await self.client.has_collection(self.collection_name)
+                else:
+                    # Assume collection doesn't exist if we can't check
+                    collection_exists = False
+            else:
+                # Assume collection doesn't exist if we can't check due to other issues
+                collection_exists = False
+
+        if not collection_exists:
             logger.info(f"Creating new collection {self.collection_name} with nullable sparse field")
             # Create schema for vector search
             schema = self.client.create_schema()
@@ -126,12 +149,16 @@ class MilvusIndex(EmbeddingIndex):
             )
             schema.add_function(bm25_function)
 
-            await self.client.create_collection(
-                self.collection_name,
-                schema=schema,
-                index_params=index_params,
-                consistency_level=self.consistency_level,
-            )
+            try:
+                await self.client.create_collection(
+                    self.collection_name,
+                    schema=schema,
+                    index_params=index_params,
+                    consistency_level=self.consistency_level,
+                )
+            except Exception as e:
+                logger.error(f"Failed to create collection {self.collection_name}: {e}")
+                raise e
 
         data = []
         for chunk, embedding in zip(chunks, embeddings, strict=False):
@@ -316,6 +343,15 @@ class MilvusVectorIOAdapter(OpenAIVectorStoreMixin, VectorIO, VectorDBsProtocolP
 
     async def initialize(self) -> None:
         self.kvstore = await kvstore_impl(self.config.kvstore)
+
+        if isinstance(self.config, RemoteMilvusVectorIOConfig):
+            logger.info(f"Connecting to Milvus server at {self.config.uri}")
+            self.client = AsyncMilvusClient(**self.config.model_dump(exclude_none=True))
+        else:
+            logger.info(f"Connecting to Milvus Lite at: {self.config.db_path}")
+            uri = os.path.expanduser(self.config.db_path)
+            self.client = AsyncMilvusClient(uri=uri)
+
         start_key = VECTOR_DBS_PREFIX
         end_key = f"{VECTOR_DBS_PREFIX}\xff"
         stored_vector_dbs = await self.kvstore.values_in_range(start_key, end_key)
@@ -329,23 +365,38 @@ class MilvusVectorIOAdapter(OpenAIVectorStoreMixin, VectorIO, VectorDBsProtocolP
                     collection_name=vector_db.identifier,
                     consistency_level=self.config.consistency_level,
                     kvstore=self.kvstore,
+                    parent_adapter=self,
                 ),
                 inference_api=self.inference_api,
             )
             self.cache[vector_db.identifier] = index
-        if isinstance(self.config, RemoteMilvusVectorIOConfig):
-            logger.info(f"Connecting to Milvus server at {self.config.uri}")
-            self.client = AsyncMilvusClient(**self.config.model_dump(exclude_none=True))
-        else:
-            logger.info(f"Connecting to Milvus Lite at: {self.config.db_path}")
-            uri = os.path.expanduser(self.config.db_path)
-            self.client = AsyncMilvusClient(uri=uri)
 
         # Load existing OpenAI vector stores into the in-memory cache
         await self.initialize_openai_vector_stores()
 
     async def shutdown(self) -> None:
-        await self.client.close()
+        if self.client:
+            await self.client.close()
+
+    async def _recreate_client(self) -> None:
+        """Recreate the AsyncMilvusClient when event loop issues occur"""
+        try:
+            if self.client:
+                await self.client.close()
+        except Exception as e:
+            logger.warning(f"Error closing old client: {e}")
+
+        if isinstance(self.config, RemoteMilvusVectorIOConfig):
+            logger.info(f"Recreating connection to Milvus server at {self.config.uri}")
+            self.client = AsyncMilvusClient(**self.config.model_dump(exclude_none=True))
+        else:
+            logger.info(f"Recreating connection to Milvus Lite at: {self.config.db_path}")
+            uri = os.path.expanduser(self.config.db_path)
+            self.client = AsyncMilvusClient(uri=uri)
+
+        for index_wrapper in self.cache.values():
+            if hasattr(index_wrapper, "index") and hasattr(index_wrapper.index, "client"):
+                index_wrapper.index.client = self.client
 
     async def register_vector_db(
         self,
@@ -357,7 +408,12 @@ class MilvusVectorIOAdapter(OpenAIVectorStoreMixin, VectorIO, VectorDBsProtocolP
             consistency_level = "Strong"
         index = VectorDBWithIndex(
             vector_db=vector_db,
-            index=MilvusIndex(self.client, vector_db.identifier, consistency_level=consistency_level),
+            index=MilvusIndex(
+                client=self.client,
+                collection_name=vector_db.identifier,
+                consistency_level=consistency_level,
+                parent_adapter=self,
+            ),
             inference_api=self.inference_api,
         )
 
@@ -376,7 +432,9 @@ class MilvusVectorIOAdapter(OpenAIVectorStoreMixin, VectorIO, VectorDBsProtocolP
 
         index = VectorDBWithIndex(
             vector_db=vector_db,
-            index=MilvusIndex(client=self.client, collection_name=vector_db.identifier, kvstore=self.kvstore),
+            index=MilvusIndex(
+                client=self.client, collection_name=vector_db.identifier, kvstore=self.kvstore, parent_adapter=self
+            ),
             inference_api=self.inference_api,
         )
         self.cache[vector_db_id] = index
diff --git a/tests/unit/providers/vector_io/remote/test_milvus.py b/tests/unit/providers/vector_io/remote/test_milvus.py
index 04bac71c2..25374e617 100644
--- a/tests/unit/providers/vector_io/remote/test_milvus.py
+++ b/tests/unit/providers/vector_io/remote/test_milvus.py
@@ -40,15 +40,12 @@ async def mock_milvus_client() -> MagicMock:
     """Create a mock Milvus client with common method behaviors."""
     client = MagicMock()
 
-    # Mock async collection operations
     client.has_collection = AsyncMock(return_value=False)  # Initially no collection
     client.create_collection = AsyncMock(return_value=None)
     client.drop_collection = AsyncMock(return_value=None)
 
-    # Mock async insert operation
     client.insert = AsyncMock(return_value={"insert_count": 10})
 
-    # Mock async search operation
     client.search = AsyncMock(
         return_value=[
             [