diff --git a/litellm/integrations/opentelemetry.py b/litellm/integrations/opentelemetry.py
index 0ec7358037..cfc2847de8 100644
--- a/litellm/integrations/opentelemetry.py
+++ b/litellm/integrations/opentelemetry.py
@@ -10,6 +10,7 @@ from litellm.types.services import ServiceLoggerPayload
 from litellm.types.utils import (
     ChatCompletionMessageToolCall,
     Function,
+    StandardCallbackDynamicParams,
     StandardLoggingPayload,
 )
 
@@ -311,6 +312,8 @@ class OpenTelemetry(CustomLogger):
         )
         _parent_context, parent_otel_span = self._get_span_context(kwargs)
 
+        self._add_dynamic_span_processor_if_needed(kwargs)
+
         # Span 1: Requst sent to litellm SDK
         span = self.tracer.start_span(
             name=self._get_span_name(kwargs),
@@ -341,6 +344,43 @@ class OpenTelemetry(CustomLogger):
         if parent_otel_span is not None:
             parent_otel_span.end(end_time=self._to_ns(datetime.now()))
 
+    def _add_dynamic_span_processor_if_needed(self, kwargs):
+        """
+        Helper method to add a span processor with dynamic headers if needed.
+
+        This allows for per-request configuration of telemetry exporters by
+        extracting headers from standard_callback_dynamic_params.
+        """
+        from opentelemetry import trace
+
+        standard_callback_dynamic_params: Optional[StandardCallbackDynamicParams] = (
+            kwargs.get("standard_callback_dynamic_params")
+        )
+        if not standard_callback_dynamic_params:
+            return
+
+        # Extract headers from dynamic params
+        dynamic_headers = {}
+
+        # Handle Arize headers
+        if standard_callback_dynamic_params.get("arize_space_key"):
+            dynamic_headers["space_key"] = standard_callback_dynamic_params.get(
+                "arize_space_key"
+            )
+        if standard_callback_dynamic_params.get("arize_api_key"):
+            dynamic_headers["api_key"] = standard_callback_dynamic_params.get(
+                "arize_api_key"
+            )
+
+        # Only create a span processor if we have headers to use
+        if len(dynamic_headers) > 0:
+            from opentelemetry.sdk.trace import TracerProvider
+
+            provider = trace.get_tracer_provider()
+            if isinstance(provider, TracerProvider):
+                span_processor = self._get_span_processor(dynamic_headers)
+                provider.add_span_processor(span_processor)
+
     def _handle_failure(self, kwargs, response_obj, start_time, end_time):
         from opentelemetry.trace import Status, StatusCode
 
@@ -445,12 +485,15 @@ class OpenTelemetry(CustomLogger):
         try:
             if self.callback_name == "arize":
                 from litellm.integrations.arize.arize import ArizeLogger
+
                 ArizeLogger.set_arize_attributes(span, kwargs, response_obj)
                 return
             elif self.callback_name == "arize_phoenix":
                 from litellm.integrations.arize.arize_phoenix import ArizePhoenixLogger
 
-                ArizePhoenixLogger.set_arize_phoenix_attributes(span, kwargs, response_obj)
+                ArizePhoenixLogger.set_arize_phoenix_attributes(
+                    span, kwargs, response_obj
+                )
                 return
             elif self.callback_name == "langtrace":
                 from litellm.integrations.langtrace import LangtraceAttributes
@@ -779,7 +822,7 @@ class OpenTelemetry(CustomLogger):
             carrier = {"traceparent": traceparent}
             return TraceContextTextMapPropagator().extract(carrier=carrier), None
 
-    def _get_span_processor(self):
+    def _get_span_processor(self, dynamic_headers: Optional[dict] = None):
         from opentelemetry.exporter.otlp.proto.grpc.trace_exporter import (
             OTLPSpanExporter as OTLPSpanExporterGRPC,
         )
@@ -799,10 +842,9 @@ class OpenTelemetry(CustomLogger):
             self.OTEL_ENDPOINT,
             self.OTEL_HEADERS,
         )
-        _split_otel_headers = {}
-        if self.OTEL_HEADERS is not None and isinstance(self.OTEL_HEADERS, str):
-            _split_otel_headers = self.OTEL_HEADERS.split("=")
-            _split_otel_headers = {_split_otel_headers[0]: _split_otel_headers[1]}
+        _split_otel_headers = OpenTelemetry._get_headers_dictionary(
+            headers=dynamic_headers or self.OTEL_HEADERS
+        )
 
         if isinstance(self.OTEL_EXPORTER, SpanExporter):
             verbose_logger.debug(
@@ -844,6 +886,20 @@ class OpenTelemetry(CustomLogger):
             )
             return BatchSpanProcessor(ConsoleSpanExporter())
 
+    @staticmethod
+    def _get_headers_dictionary(headers: Optional[Union[str, dict]]) -> dict:
+        """
+        Convert a string or dictionary of headers into a dictionary of headers.
+        """
+        _split_otel_headers = {}
+        if headers:
+            if isinstance(headers, str):
+                _split_otel_headers = headers.split("=")
+                _split_otel_headers = {_split_otel_headers[0]: _split_otel_headers[1]}
+            elif isinstance(headers, dict):
+                _split_otel_headers = headers
+        return _split_otel_headers
+
     async def async_management_endpoint_success_hook(
         self,
         logging_payload: ManagementEndpointLoggingPayload,