diff --git a/litellm/__init__.py b/litellm/__init__.py
index 9e7c26186..52ef19b57 100644
--- a/litellm/__init__.py
+++ b/litellm/__init__.py
@@ -76,6 +76,8 @@ caching_with_models: bool = (
 cache: Optional[Cache] = (
     None  # cache object <- use this - https://docs.litellm.ai/docs/caching
 )
+default_in_memory_ttl: Optional[float] = None
+default_redis_ttl: Optional[float] = None
 model_alias_map: Dict[str, str] = {}
 model_group_alias_map: Dict[str, str] = {}
 max_budget: float = 0.0  # set the max budget across all providers
diff --git a/litellm/caching.py b/litellm/caching.py
index 301acd593..197dc0cc5 100644
--- a/litellm/caching.py
+++ b/litellm/caching.py
@@ -845,8 +845,10 @@ class DualCache(BaseCache):
         # If redis_cache is not provided, use the default RedisCache
         self.redis_cache = redis_cache
 
-        self.default_in_memory_ttl = default_in_memory_ttl
-        self.default_redis_ttl = default_redis_ttl
+        self.default_in_memory_ttl = (
+            default_in_memory_ttl or litellm.default_in_memory_ttl
+        )
+        self.default_redis_ttl = default_redis_ttl or litellm.default_redis_ttl
 
     def set_cache(self, key, value, local_only: bool = False, **kwargs):
         # Update both Redis and in-memory cache
@@ -956,6 +958,8 @@ class Cache:
         password: Optional[str] = None,
         namespace: Optional[str] = None,
         ttl: Optional[float] = None,
+        default_in_memory_ttl: Optional[float] = None,
+        default_in_redis_ttl: Optional[float] = None,
         similarity_threshold: Optional[float] = None,
         supported_call_types: Optional[
             List[
@@ -1055,6 +1059,14 @@ class Cache:
         self.redis_flush_size = redis_flush_size
         self.ttl = ttl
 
+        if self.type == "local" and default_in_memory_ttl is not None:
+            self.ttl = default_in_memory_ttl
+
+        if (
+            self.type == "redis" or self.type == "redis-semantic"
+        ) and default_in_redis_ttl is not None:
+            self.ttl = default_in_redis_ttl
+
         if self.namespace is not None and isinstance(self.cache, RedisCache):
             self.cache.namespace = self.namespace
 
diff --git a/litellm/proxy/proxy_server.py b/litellm/proxy/proxy_server.py
index 51e425edc..7822bc61d 100644
--- a/litellm/proxy/proxy_server.py
+++ b/litellm/proxy/proxy_server.py
@@ -1908,6 +1908,12 @@ class ProxyConfig:
         global redis_usage_cache
         from litellm import Cache
 
+        if "default_in_memory_ttl" in cache_params:
+            litellm.default_in_memory_ttl = cache_params["default_in_memory_ttl"]
+
+        if "default_redis_ttl" in cache_params:
+            litellm.default_redis_ttl = cache_params["default_in_redis_ttl"]
+
         litellm.cache = Cache(**cache_params)
 
         if litellm.cache is not None and isinstance(litellm.cache.cache, RedisCache):